Prevalence of High Risk HPV Infection in Different Cervical Cytological Features in Thailand

Cervical cancer is the second leading cancer among Thai women, the incidence rate was 16.7/100,00 (Khuhaprema, 2013). Cervical cancer screening based on the Papanicolaou (Pap) smear test has been credited with a significant reduction in the incidence of this disease. For a several decades, most of hospitals in Thailand using this method for cervical cancer screening. Today, certain types of human papillomavirus (HPV) have now conclusively been shown as a necessary cause of cervical cancer (Wallboom, 1999). In addition, epidemiologic studies have shown a strong association between high-risk HPV types and the development of high-grade cervical intraepithelial neoplasias (CIN) (Kjaer, 2002; Sclect, 2001; Woodma, 2001). Alternative technologies such as liquid based cytology or human papillomavirus (HPV) screening or vaccination have been proposed as possible means to improve prevention of cervical cancer. (IARC, 2005; 2007) According to the ASCCP (American Society for